Clinical and Economic Impact of Community-Onset Urinary Tract Infections Caused by ESBL-Producing Klebsiella pneumoniae Requiring Hospitalization in Spain: An Observational Cohort Study

High Prevalence of ESBL-Producing Klebsiella pneumoniae Causing Community-Onset Infections in China

The aim of this work was to investigate the epidemiological and genetic characteristics of ESBL-producing Klebsiella pneumoniae (ESBL-Kp) causing community-onset infections. K. pneumoniae isolates were collected from 31 Chinese secondary hospitals between August 2010 and 2011. Genes encoding ESBL and AmpC beta-lactamases were detected by PCR. The isolates were assigned to sequence types (STs) u...

Clinical and bacteriological effects of pivmecillinam for ESBL-producing Escherichia coli or Klebsiella pneumoniae in urinary tract infections.

OBJECTIVES The prevalence of urinary tract infections (UTIs) caused by extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae is increasing and the therapeutic options are limited, especially in primary care. Recent indications have suggested pivmecillinam to be a suitable option. Here, we evaluated the clinical and bacteriological effects of pivmecillinam in UTIs caused by ESBL-prod...

Clinical impact of infections caused by ESBL-producing E. coli and K. pneumoniae.

The outcome of infections occurring at different anatomic sites caused by ESBL-producing E. coli or K. pneumoniae was retrospectively analysed for a 3-y period. 23 cases were compared to 46 controls with infections caused by third-generation cephalosporin-susceptible strains matched by age, severity of illness and duration of hospitalization before onset of infection. Only 27.8% of cases receiv...

Distribution of nosocomial infections caused by Klebsiella pneumoniae ESBL strain

prevalence of extended-spectrum beta-lactamase-producing klebsiella pneumoniae isolates in nosocomial and community-acquired urinary tract infections

background klebsiella pneumoniae is a family member of enterobacteriaceae. isolates of k. pneumoniae produce enzymes that cause decomposition of third generation cephalosporins. these enzymes are known as extended-spectrum beta-lactamase (esbl). resistance of k. pneumoniae to beta-lactamase antibiotics is commonly mediated by beta-lactamase genes. objectives the aim of this study was to identif...